Description

5-Bromo-3-Chloro-2-Pyridinecarboxylic Acid Methyl Ester is a high-purity pyridine derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized, halogenated pyridine scaffold essential for constructing complex molecules with targeted biological or material properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Pyridinecarboxylic Acid Methyl Ester
CAS No.	1214336-41-0
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	Methyl 5-bromo-3-chloropicolinate; 5-Bromo-3-chloro-2-pyridinecarboxylic acid methyl ester; 3-Chloro-5-bromopicolinic acid methyl ester; Methyl 5-bromo-3-chloro-2-pyridinecarboxylate; 2-Pyridinecarboxylic acid, 5-bromo-3-chloro-, methyl ester; 5-Bromo-3-chloro-picolinic acid methyl ester; Methyl 3-chloro-5-bromopicolinate
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Chloro-2-Pyridinecarboxylic Acid Methyl Ester adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.