Description

(3-Fluoro-2-Nitrophenyl)Methanol, also known as 3-Fluoro-2-Nitrobenzyl Alcohol, is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitro and a hydroxymethyl group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug molecules, where the fluorine atom can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluoronitrobenzyl moiety for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and other advanced materials with unique electronic or surface properties.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing novel fluorinated dyes and pigments with specific color fastness and light-absorption characteristics.
• Custom Synthesis and Contract Research: An essential reagent for custom synthesis houses and CROs (Contract Research Organizations) working on client-specific fluorination projects.

Basic Information

Product Name	(3-Fluoro-2-Nitrophenyl)Methanol / 3-Fluoro-2-Nitrobenzyl Alcohol
CAS No.	1214323-11-1
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	3-Fluoro-2-Nitrobenzyl Alcohol; (3-Fluoro-2-Nitrophenyl)Methanol; 2-Nitro-3-fluorobenzyl Alcohol; 1-(Hydroxymethyl)-3-fluoro-2-nitrobenzene; 3-Fluoro-2-nitrobenzenemethanol; α-Hydroxymethyl-3-fluoro-2-nitrobenzene; Benzenemethanol, 3-fluoro-2-nitro-
EINECS	Contact for details

Quality Control

Every batch of (3-Fluoro-2-Nitrophenyl)Methanol undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and industrial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store this material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.