Description

(R)-2-Methyl-5-(2-Pyrrolidinyl)-Pyridine is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) with specific stereochemical requirements. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a ligand or precursor in catalytic asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for commercial drug manufacturing.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-2-Methyl-5-(2-Pyrrolidinyl)-Pyridine
CAS No.	1213165-87-7
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(R)-2-Methyl-5-(pyrrolidin-2-yl)pyridine; (R)-2-(5-Methylpyridin-2-yl)pyrrolidine; (R)-2-(5-Methyl-2-pyridinyl)pyrrolidine; (R)-2-Methyl-5-(2-pyrrolidinyl)pyridine; (R)-5-Methyl-2-(pyrrolidin-2-yl)pyridine; (R)-ANi-1; (R)-ANi1; (R)-2-(5-Methylpyridin-2-yl)-1-pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-2-Methyl-5-(2-Pyrrolidinyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.