Description

(1S)-1-(5-Fluoro(3-Pyridyl))Ethylamine is a high-purity chiral amine building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical intermediate for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating targeted molecules with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the specific stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Process Chemistry & Scale-Up: Critical for route scouting and optimization during the transition from laboratory to pilot and commercial-scale manufacturing.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this specialized building block.

Basic Information

Product Name	(1S)-1-(5-Fluoro(3-Pyridyl))Ethylamine
CAS No.	1213045-95-4
Molecular Formula	C7H9FN2
Molecular Weight	140.16 g/mol
Synonyms	(S)-1-(5-Fluoropyridin-3-yl)ethan-1-amine; (1S)-1-(5-Fluoro-3-pyridinyl)ethylamine; 5-Fluoro-3-pyridineethanamine, (αS)-; (S)-α-Methyl-5-fluoro-3-pyridinemethanamine; (S)-1-(5-Fluoropyridin-3-yl)ethylamine; (S)-5-Fluoro-3-(1-aminoethyl)pyridine; (1S)-1-(5-Fluoropyridin-3-yl)ethanamine
EINECS	Contact for details

Quality Control

Our (1S)-1-(5-Fluoro(3-Pyridyl))Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.