Description

5-Bromo-2-Ethyl-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo, nitro, and ethyl functionalities into pyridine-based structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogen and nitro groups for structural diversification.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and photoactive materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro group activates the pyridine ring for substitution reactions, enabling further functionalization.

Basic Information

Product Name	5-Bromo-2-Ethyl-3-Nitropyridine
CAS No.	1211591-74-0
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	3-Nitro-5-bromo-2-ethylpyridine; 2-Ethyl-5-bromo-3-nitropyridine; 5-Bromo-2-ethyl-3-nitro-pyridine; Pyridine, 5-bromo-2-ethyl-3-nitro-; 1211591-74-0
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Ethyl-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality assurance ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.