Description

4-(Difluoromethyl)-1H-Pyrazole is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique difluoromethyl-substituted pyrazole core makes it a critical intermediate for developing novel active compounds with enhanced properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting various disease areas.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrazole moiety.
• Material Science Research: Used in the development of advanced functional materials, including ligands for catalysis and components for electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for studying biological systems and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-(Difluoromethyl)-1H-Pyrazole
CAS No.	1211589-69-3
Molecular Formula	C4H4F2N2
Molecular Weight	118.09 g/mol
Synonyms	4-(Difluoromethyl)-1H-pyrazole; 1H-Pyrazole, 4-(difluoromethyl)-; 4-(Difluoromethyl)pyrazole; 4-Difluoromethyl-1H-pyrazole; 4-Difluoromethylpyrazole; Difluoromethylpyrazole
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.