Description

5-(Chloromethyl)-2-(Difluoromethoxy)Pyridine is a high-value, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated methoxy structure enables precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, leveraging its difluoromethoxy group for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Custom Chemical Synthesis: Provides a flexible starting point for contract research organizations (CROs) and CDMOs to build custom molecules for client projects.

Basic Information

Product Name	5-(Chloromethyl)-2-(Difluoromethoxy)Pyridine
CAS No.	1211584-92-7
Molecular Formula	C7H6ClF2NO
Molecular Weight	193.58 g/mol
Synonyms	2-(Difluoromethoxy)-5-(chloromethyl)pyridine; 5-(Chloromethyl)-2-(difluoromethoxy)pyridine; Pyridine, 5-(chloromethyl)-2-(difluoromethoxy)-; 1211584-92-7
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)-2-(Difluoromethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.