Description

5-Ethynylpyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block featuring both an ethynyl and a nitrile group on a pyridine scaffold. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, receptor modulators, and other small-molecule drug candidates.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with new modes of action.
• Ligand Synthesis: Serves as a precursor for creating sophisticated chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of conductive polymers, organic semiconductors, and advanced polymeric materials.
• Chemical Biology: Useful for creating probes and tags via click chemistry (copper-catalyzed azide-alkyne cycloaddition) due to the terminal alkyne group.
• Academic & Contract Research: A versatile reagent for exploratory organic synthesis and methodology development in university and CRO laboratories.

Basic Information

Product Name	5-Ethynylpyridine-2-Carbonitrile
CAS No.	1211584-19-8
Molecular Formula	C8H4N2
Molecular Weight	128.13 g/mol
Synonyms	2-Cyano-5-ethynylpyridine; 5-Ethynyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 5-ethynyl-; 5-Ethynylpicolinonitrile
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 5-Ethynylpyridine-2-Carbonitrile adheres to internal quality management systems, with purity and identity verified by advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and impurity profiles is provided with each batch to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.