Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 4-Chloro- is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams and fine chemical manufacturers need this intermediate to synthesize potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its fused pyrrolopyridine core.
• Material Science Precursor: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 4-Chloro-
CAS No.	1211583-37-7
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	4-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Chloro-7-azaindole-2-carboxylic acid; 4-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Chloro-2-carboxy-7-azaindole; 4-Chloro-7-aza-1H-indole-2-carboxylic acid; 4-Chloro-1H-7-azaindole-2-carboxylic acid; 4-Chloro-2-carboxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 4-Chloro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.