Description

4-Chloro-3-Fluoro-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique fused pyrrolopyridine core, substituted with halogen atoms, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of new drug candidates, particularly in oncology, CNS disorders, and antiviral therapies.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Chloro-3-Fluoro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1211582-49-8
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	4-Chloro-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-3-fluoro-; 4-Chloro-3-fluoro-7-azaindole; 3-Fluoro-4-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-3-fluoro-1H-7-azaindole; 4-Chloro-3-fluoro-7-aza-indole; 4-Chloro-3-fluoro-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Fluoro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for research and development. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and MS to confirm identity, purity, and the absence of critical impurities. Our quality commitment aligns with the standards expected by pharmaceutical and agrochemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.