Description

3-Pyridinecarboxylic Acid, 4,6-Dichloro-2-(Trifluoromethyl)-, Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced chemical synthesis. Its value lies in the strategic combination of halogen and trifluoromethyl substituents on the pyridine core, which are crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• As a key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) and metabolic diseases.
• As a versatile agrochemical intermediate for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• As a specialized building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• In material science research for the synthesis of advanced organic ligands, metal-organic frameworks (MOFs), or functional polymers.
• For use in custom synthesis and contract manufacturing for clients requiring tailored, high-value chemical entities.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 4,6-Dichloro-2-(Trifluoromethyl)-, Ethyl Ester
CAS No.	1211580-73-2
Molecular Formula	C9H6Cl2F3NO2
Molecular Weight	288.05 g/mol
Synonyms	Ethyl 4,6-dichloro-2-(trifluoromethyl)nicotinate; 4,6-Dichloro-2-(trifluoromethyl)nicotinic Acid Ethyl Ester; Ethyl 4,6-Dichloro-2-(trifluoromethyl)pyridine-3-carboxylate; 4,6-Dichloro-2-trifluoromethyl-nicotinic Acid Ethyl Ester; 3-Carbethoxy-4,6-dichloro-2-(trifluoromethyl)pyridine; CAS 1211580-73-2
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 4,6-Dichloro-2-(Trifluoromethyl)-, Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.