Description

4-Bromo-5-Chloro-2-Fluoro-Pyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which enables precise structural modifications in complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its halogenated structure contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to the electron-withdrawing nature of the halogen atoms.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Fluoro-Pyridine
CAS No.	1211580-71-0
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	2-Fluoro-4-bromo-5-chloropyridine; 5-Chloro-4-bromo-2-fluoropyridine; 4-Bromo-5-chloro-2-fluoropyridine; Pyridine, 4-bromo-5-chloro-2-fluoro-; 2-Fluoro-5-chloro-4-bromopyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Fluoro-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.