Description

Palbociclib-030 CAS NO 1211541-02-4 is a high-purity pharmaceutical intermediate and reference standard, specifically a key derivative of the active pharmaceutical ingredient Palbociclib. This compound is critical for research, development, and quality control processes in the production of targeted cancer therapeutics. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in oncology drug development and regulatory compliance testing.

Application

• Primary use as a reference standard for analytical method development and validation in HPLC and LC-MS systems.
• Critical pharmaceutical intermediate in the synthesis and scale-up of Palbociclib API.
• Essential material for impurity profiling and stability studies of oncology drug products.
• Used in preclinical and clinical research to study drug metabolism and pharmacokinetics (DMPK).
• Serves as a building block for the derivatization and synthesis of novel CDK4/6 inhibitor analogs.
• Supports quality control (QC) and quality assurance (QA) laboratories in ensuring batch-to-batch consistency.

Basic Information

Product Name	Palbociclib-030
CAS No.	1211541-02-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Palbociclib Impurity 30; Palbociclib Related Compound 30; 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Intermediate; Palbociclib Derivative; CDK4/6 Inhibitor Intermediate; IBRANCE Impurity
EINECS	Contact for details

Quality Control

Our Palbociclib-030 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent screening to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.