Description

2-Bromo-4-Fluoro-5-Methylpyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on the pyridine ring, makes it an indispensable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for constructing complex organic frameworks.
• Chemical Biology: Employed as a probe or labeling agent due to the reactivity of the bromine atom in cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring specific halogenated pyridine motifs.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Methylpyridine
CAS No.	1211537-29-9
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	5-Methyl-2-bromo-4-fluoropyridine; 4-Fluoro-5-methyl-2-bromopyridine; 2-Bromo-4-fluoro-5-methyl-pyridine; Pyridine, 2-bromo-4-fluoro-5-methyl-; 1211537-29-9; 2-Bromo-4-fluoro-5-methylpyridine; 4-Fluoro-2-bromo-5-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluoro-5-Methylpyridine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.