Description

6-Bromo-5-Trifluoromethyl-Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents on a pyridine-carboxylic acid core, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for targeted therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for designing novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	6-Bromo-5-Trifluoromethyl-Pyridine-2-Carboxylic Acid
CAS No.	1211537-01-7
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-bromo-5-(trifluoromethyl)-; 6-Bromo-5-(trifluoromethyl)picolinic acid; 5-Trifluoromethyl-6-bromopicolinic acid; 6-Bromo-5-trifluoromethylpicolinic acid; 6-Bromo-5-trifluoromethyl-2-pyridinecarboxylic acid; 2-Bromo-3-carboxy-4-trifluoromethylpyridine; BTFP Acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Trifluoromethyl-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.