Description

2-Bromo-5-Chloro-3-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen atoms for further cross-coupling or substitution reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for targeted therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with specific modes of action.
• Material Science Building Block: Employed in the creation of organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Serves as an excellent substrate for Suzuki, Stille, and Negishi couplings due to the presence of bromine and iodine atoms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research.
• Ligand Synthesis: Acts as a starting material for the preparation of complex polydentate ligands used in catalysis.

Basic Information

Product Name	2-Bromo-5-Chloro-3-Iodopyridine
CAS No.	1211535-24-8
Molecular Formula	C5H2BrClIN
Molecular Weight	318.34 g/mol
Synonyms	3-Iodo-2-bromo-5-chloropyridine; 5-Chloro-2-bromo-3-iodopyridine; 2-Bromo-5-chloro-3-iodopyridine; Pyridine, 2-bromo-5-chloro-3-iodo-; 1211535-24-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-3-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.