Description

5-Chloromethyl-3-Fluoro-2-Methoxy-Pyridine is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of reactive chloromethyl and fluorine substituents on the methoxypyridine scaffold, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to synthesize complex pyridine-based ligands for transition metal catalysis and organocatalysts.
• Material Science Precursor: Intermediate in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A versatile starting material for custom chemical synthesis and scale-up services under cGMP or ISO standards.
• Research & Development: A valuable tool for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	5-Chloromethyl-3-Fluoro-2-Methoxy-Pyridine
CAS No.	1211535-18-0
Molecular Formula	C7H7ClFNO
Molecular Weight	175.59 g/mol
Synonyms	2-Methoxy-3-fluoro-5-(chloromethyl)pyridine; 3-Fluoro-2-methoxy-5-(chloromethyl)pyridine; 5-(Chloromethyl)-3-fluoro-2-methoxypyridine; 2-Methoxy-3-fluoropyridine-5-methyl chloride; 3-Fluoro-2-methoxypyridine-5-methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chloromethyl-3-Fluoro-2-Methoxy-Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.