Description

3-Bromo-5-Chloro-4-(Trifluoromethyl)Pyridine is a high-purity halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty chemicals, liquid crystals, and functional materials.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry and drug discovery programs.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	3-Bromo-5-Chloro-4-(Trifluoromethyl)Pyridine
CAS No.	1211528-99-2
Molecular Formula	C7H2BrClF3N
Molecular Weight	274.45 g/mol
Synonyms	3-Bromo-5-chloro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-3-bromo-5-chloropyridine; 5-Chloro-3-bromo-4-(trifluoromethyl)pyridine; Pyridine, 3-bromo-5-chloro-4-(trifluoromethyl)-; 3-Bromo-5-chloro-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.