Description

3-Fluoro-6-Methylpyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its unique molecular structure, featuring a fluorine substituent and a nitrile group on a methylated pyridine core, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for developing fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic systems used in fine chemical manufacturing.
• Material Science Research: Acts as a building block for developing functional polymers, liquid crystals, or organic electronic materials due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3-Fluoro-6-Methylpyridine-2-Carbonitrile
CAS No.	1211527-37-5
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	2-Cyano-3-fluoro-6-methylpyridine; 6-Methyl-3-fluoropyridine-2-carbonitrile; 3-Fluoro-6-picolinonitrile; 3-Fluoro-6-methyl-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 3-fluoro-6-methyl-
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-6-Methylpyridine-2-Carbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (HPLC, GC, NMR) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.