Description

5H - Pyrido[2,3 - B]Azepine, 2 - Chloro - 6,7,8,9 - Tetrahydro is a high-purity, advanced pharmaceutical intermediate belonging to the azepine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures due to its fused pyridoazepine core and reactive chloro substituent.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic & Industrial Research: Employed in exploratory chemistry to study structure-activity relationships (SAR) and develop new synthetic methodologies.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	5H - Pyrido[2,3 - B]Azepine, 2 - Chloro - 6,7,8,9 - Tetrahydro
CAS No.	1211526-68-9
Molecular Formula	C11H13ClN2
Molecular Weight	208.69 g/mol
Synonyms	2-Chloro-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepine; 2-Chloro-5H-pyrido[2,3-b]azepine, 6,7,8,9-tetrahydro-; 2-Chloro-6,7,8,9-tetrahydro-5H-azepino[2,3-b]pyridine; 5H-Pyrido[2,3-b]azepine, 2-chloro-6,7,8,9-tetrahydro-; 1211526-68-9; 2-Chloro-5H-pyrido[2,3-b]azepine; Tetrahydro-pyridoazepine chloride derivative
EINECS	Contact for details

Quality Control

Every batch of 5H - Pyrido[2,3 - B]Azepine, 2 - Chloro - 6,7,8,9 - Tetrahydro is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.