Description

2-(2-Bromopyridin-3-Yl)Acetonitrile is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive nitrile and bromine functional groups, enabling precise molecular construction for complex target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and heterocyclic compound libraries.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyridine core for bioactive molecule design.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Nitrile Transformation Chemistry: The acetonitrile moiety can be converted into various functional groups such as acids, amides, and tetrazoles.

Basic Information

Product Name	2-(2-Bromopyridin-3-Yl)Acetonitrile
CAS No.	1211523-71-5
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	2-(2-Bromo-3-pyridinyl)acetonitrile; (2-Bromopyridin-3-yl)acetonitrile; 3-Pyridineacetonitrile, 2-bromo-; 2-Bromo-3-pyridineacetonitrile; 2-Bromonicotinonitrile (related but not identical, often confused); α-(2-Bromopyridin-3-yl)acetonitrile; 2-Bromo-3-cyanomethylpyridine
EINECS	Contact for details

Quality Control

Our 2-(2-Bromopyridin-3-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting the exact specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.