Description

2-Bromo-4-Chloro-3-Methylpyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogenated pyridine core provides specific bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-Bromo-4-Chloro-3-Methylpyridine
CAS No.	1211521-46-8
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	4-Chloro-2-bromo-3-methylpyridine; 3-Methyl-2-bromo-4-chloropyridine; 2-Bromo-4-chloro-3-picoline; Pyridine, 2-bromo-4-chloro-3-methyl-; 1211521-46-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.