Description

4-Chloro-5-(Trifluoromethyl)Nicotinic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. This compound is prized for its unique trifluoromethyl and chloro substituents, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic frameworks in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	4-Chloro-5-(Trifluoromethyl)Nicotinic Acid
CAS No.	1211520-84-1
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	4-Chloro-5-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-chloro-5-(trifluoromethyl)-; 4-Chloro-5-trifluoromethylnicotinic acid; 4-Chloro-5-trifluoromethyl-3-pyridinecarboxylic acid; 1211520-84-1; Nicotinic acid, 4-chloro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-5-(Trifluoromethyl)Nicotinic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We are committed to meeting the exacting standards required for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.