Description

3-Bromo-6-Methyl-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents, makes it an indispensable intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials where the trifluoromethyl group modifies physical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Fluorine Chemistry Building Block: The stable trifluoromethyl group is utilized to incorporate fluorine atoms into molecules to enhance metabolic stability, lipophilicity, and bioavailability.

Basic Information

Item	Details
Product Name	3-Bromo-6-Methyl-2-(Trifluoromethyl)Pyridine
CAS No.	1211517-98-4
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-(Trifluoromethyl)-3-bromo-6-methylpyridine; 3-Bromo-2-(trifluoromethyl)-6-picoline; 6-Methyl-3-bromo-2-(trifluoromethyl)pyridine; 3-Bromo-6-methyl-2-trifluoromethylpyridine; 2-Trifluoromethyl-3-bromo-6-methylpyridine; 3-Bromo-2-trifluoromethyl-6-methylpyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Methyl-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.