Description

2-Bromo-3-Chloro-6-Fluoropyridine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of the bromo substituent.
• Nucleophilic Aromatic Substitution: The fluorine and chlorine atoms offer sites for selective displacement with various nucleophiles, enabling diverse chemical modifications.

Basic Information

Product Name	2-Bromo-3-Chloro-6-Fluoropyridine
CAS No.	1211515-01-3
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	2-Bromo-3-chloro-6-fluoropyridine; 3-Chloro-2-bromo-6-fluoropyridine; 6-Fluoro-3-chloro-2-bromopyridine; Pyridine, 2-bromo-3-chloro-6-fluoro-; 2-Bromo-3-chloro-6-fluoro-pyridine; 1211515-01-3
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloro-6-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.