Description

2-Amino-5-(Trifluoromethyl)Pyridine-3-Carbonitrile is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a trifluoromethyl substituent, makes it an essential intermediate for creating compounds with tailored biological and physical properties. This product is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the stability imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Building block for the development of organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Amino-5-(Trifluoromethyl)Pyridine-3-Carbonitrile
CAS No.	1211514-97-4
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)nicotinonitrile; 3-Cyano-5-(trifluoromethyl)pyridin-2-amine; 5-(Trifluoromethyl)-2-aminopyridine-3-carbonitrile; 2-Amino-3-cyano-5-(trifluoromethyl)pyridine; 2-Pyridinamine, 3-cyano-5-(trifluoromethyl)-; Nicotinonitrile, 2-amino-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(Trifluoromethyl)Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.