Description

5-Carboethoxy-2’-Deoxycytidine is a modified nucleoside derivative, specifically a 2'-deoxycytidine analog with a carboethoxy substituent at the 5-position. This compound is a crucial intermediate in the synthesis of oligonucleotides and modified nucleic acids for advanced research and therapeutic applications. It is primarily used by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production.

Application

• Oligonucleotide Synthesis: A key phosphoramidite building block for the solid-phase synthesis of modified DNA strands.
• Antiviral & Anticancer Drug Development: Serves as a precursor for prodrugs and active pharmaceutical ingredients (APIs) targeting viral replication and cancer cell proliferation.
• Molecular Biology Research: Used to incorporate specific modifications into DNA probes and primers for studying nucleic acid interactions and enzyme mechanisms.
• Diagnostic Reagents: Employed in the manufacture of labeled nucleotides for sequencing, PCR, and microarray technologies.
• Bioconjugation: The reactive ester group facilitates conjugation with other molecules for creating targeted delivery systems or diagnostic tools.

Basic Information

Product Name	5-Carboethoxy-2’-Deoxycytidine
CAS No.	1210427-55-6
Molecular Formula	C12H17N3O6
Molecular Weight	299.28 g/mol
Synonyms	5-(Ethoxycarbonyl)-2'-deoxycytidine; 2'-Deoxy-5-ethoxycarbonylcytidine; 5-Carbethoxy-2'-deoxycytidine; 5-Ethoxycarbonyl-2'-deoxycytidine; dCEt; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(ethoxycarbonyl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-Carboethoxy-2’-Deoxycytidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.