Description

3-Bromo-5-tert-Butylpyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a bulky tert-butyl group, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting compounds.
• Chemical Biology Probes: Useful for modifying peptides and proteins or creating molecular probes for studying biological systems.
• Custom Synthesis and R&D: A high-purity building block for contract research organizations (CROs) and academic laboratories engaged in novel compound library synthesis.

Basic Information

Product Name	3-Bromo-5-tert-Butylpyridine
CAS No.	1209458-34-3
Molecular Formula	C9H12BrN
Molecular Weight	214.10 g/mol
Synonyms	5-tert-Butyl-3-bromopyridine; 3-Bromo-5-(1,1-dimethylethyl)pyridine; 3-Bromo-5-(tert-butyl)pyridine; Pyridine, 3-bromo-5-(1,1-dimethylethyl)-; 3-Bromo-5-tert-butyl-pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-tert-Butylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.