Description

5H-Imidazo[4,5-C]Pyridine-5-Carboxylic Acid, 2-Bromo-3,4,6,7-Tetrahydro-, 1,1-Dimethylethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a complex heterocyclic core structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in developing innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Synthesis: A potential precursor in the development of protease inhibitors due to its imidazopyridine scaffold.
• Kinase Inhibitor Development: Employed in the creation of kinase inhibitor libraries for high-throughput screening.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5H-Imidazo[4,5-C]Pyridine-5-Carboxylic Acid, 2-Bromo-3,4,6,7-Tetrahydro-, 1,1-Dimethylethyl Ester
CAS No.	1208098-53-6
Molecular Formula	C13H18BrN3O2
Molecular Weight	328.21 g/mol
Synonyms	tert-Butyl 2-bromo-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxylate; 2-Bromo-3,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5-carboxylic acid 1,1-dimethylethyl ester; 2-Bromo-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 2-bromo-4,5,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carboxylate; 1208098-53-6; 2-Bromo-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development under cGMP (current Good Manufacturing Practice) guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.