Description

2-Chloro-5-Methyl-Pyridine-3-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile electrophile, enabling the introduction of the sulfonamide moiety into target molecules, which is essential for modulating biological activity and physical properties. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with sulfonamide functionalities.
• Material Science Research: Employed in the synthesis of functional polymers, ligands for catalysis, and advanced organic materials.
• Chemical Biology Probes: Serves as a reagent for labeling and modifying biomolecules to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Chloro-5-Methyl-Pyridine-3-Sulfonyl Chloride
CAS No.	1208081-98-4
Molecular Formula	C7H7Cl2NO2S
Molecular Weight	240.11 g/mol
Synonyms	3-Chlorosulfonyl-2-chloro-5-methylpyridine; 2-Chloro-5-methylpyridine-3-sulfonyl chloride; 5-Methyl-2-chloropyridine-3-sulfonyl chloride; 3-Pyridinesulfonyl chloride, 2-chloro-5-methyl-; 2-Chloro-5-methyl-3-pyridinesulfonyl chloride; 2-Chloro-5-methyl-3-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Methyl-Pyridine-3-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure high chemical purity and lot-to-lot consistency, suitable for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.