Description

2-Chloro-4-Methyl-Pyridine-3-Sulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its reactive sulfonyl chloride and chloro-substituted pyridine structure makes it a critical building block for constructing complex molecules with precision. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its pyridine core for biological activity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and other specialty materials.
• Chemical Derivatization: The reactive sulfonyl chloride group is utilized for introducing sulfonamide functionalities into target molecules, a common motif in drug discovery.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs) serving the life sciences industry.

Basic Information

Product Name	2-Chloro-4-Methyl-Pyridine-3-Sulfonyl Chloride
CAS No.	1208081-91-7
Molecular Formula	C7H7Cl2NO2S
Molecular Weight	240.11 g/mol
Synonyms	3-Chlorosulfonyl-2-chloro-4-methylpyridine; 2-Chloro-4-methylpyridine-3-sulfonyl chloride; 4-Methyl-2-chloropyridine-3-sulfonyl chloride; 3-Pyridinesulfonyl chloride, 2-chloro-4-methyl-; 2-Chloro-4-methyl-3-pyridinesulfonyl chloride; 1208081-91-7; 2-Chloro-4-methylpyridine-3-sulfonylchloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Methyl-Pyridine-3-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and high purity for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.