Description

2,5-Dichloro-Pyridine-3-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated pyridine structure. This compound matters for its critical role as a versatile building block in the synthesis of complex molecules, enabling the introduction of the sulfonamide pharmacophore. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, particularly sulfonamide-based drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide-based active pharmaceutical ingredients (APIs), including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that incorporate sulfonamide moieties for enhanced efficacy.
• Material Science Research: Serves as a precursor for creating functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Employed in the development of chemical probes and affinity labels for studying protein function and biological pathways.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments, particularly those requiring halogenated heterocyclic structures.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	2,5-Dichloro-Pyridine-3-Sulfonyl Chloride
CAS No.	1208081-36-0
Molecular Formula	C5H2Cl3NO2S
Molecular Weight	246.50 g/mol
Synonyms	3,6-Dichloropyridine-4-sulfonyl chloride; 2,5-Dichloropyridine-3-sulfonyl chloride; 4-Pyridinesulfonyl chloride, 3,6-dichloro-; 3,6-Dichloro-4-pyridinesulfonyl chloride; 2,5-Dichloro-3-pyridinesulfonyl chloride; 3-Pyridinesulfonyl chloride, 2,5-dichloro-; 2,5-Dichloro-3-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-Pyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.