Description

Scy-078 is a novel antifungal agent belonging to the triterpenoid class, specifically a semisynthetic derivative of enfumafungin. This compound is of significant commercial and research interest due to its unique mechanism of action, targeting the fungal cell wall synthesis enzyme β-(1,3)-D-glucan synthase. Industries requiring advanced antifungal solutions, particularly in pharmaceutical R&D for invasive fungal infections, rely on high-purity Scy-078 CAS NO 1207753-03-4 for development and manufacturing.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the research, development, and production of novel antifungal medications.
• Biomedical Research: A critical reference standard and tool compound for studying fungal pathogenesis and resistance mechanisms in academic and institutional labs.
• Preclinical & Clinical Development: Serves as the key material for formulation studies, pharmacokinetic/pharmacodynamic (PK/PD) modeling, and clinical trial material (CTM) manufacturing.
• Antifungal Susceptibility Testing: Used to establish minimum inhibitory concentration (MIC) values against various Candida and Aspergillus species.
• Combinatorial Therapy Research: Investigated for synergistic effects when combined with other antifungal classes to overcome drug resistance.

Basic Information

Product Name	Scy-078
CAS No.	1207753-03-4
Molecular Formula	C35H54N2O8
Molecular Weight	630.82 g/mol
Synonyms	Ibrexafungerp; SCY-078; (1R,4aR,5S,6R,8aS,10S,10aR,10bS)-5,6,10-Trihydroxy-4a,7,7,10a-tetramethyl-3-oxo-1-(2-oxo-2-[(2R,3R)-3-(trifluoromethyl)oxiran-2-yl]ethyl)dodecahydro-2H-naphtho[2,1-b]pyran-8a(6H)-carboxylic acid; MK-3118; Enfumafungin derivative
EINECS	Contact for details

Quality Control

Our Scy-078 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical intermediates and reference standards. A Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.