Description

Ethyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Synthesis: Employed in multi-step synthetic routes for the production of potential active pharmaceutical ingredients.
• Biochemical Tool Compound: Serves as a research tool in biochemical assays and pharmacological studies to investigate specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	Ethyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate
CAS No.	1207253-96-0
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	Ethyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate; 1,7-Naphthyridine-3-carboxylic acid, 5,6,7,8-tetrahydro-, ethyl ester; Ethyl 5,6,7,8-tetrahydro[1,7]naphthyridine-3-carboxylate; 5,6,7,8-Tetrahydro-1,7-naphthyridine-3-carboxylic acid ethyl ester; 3-Carbethoxy-5,6,7,8-tetrahydro-1,7-naphthyridine; CAS 1207253-96-0
EINECS	Contact for details

Quality Control

Our Ethyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.