Description

Ethyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate Hydrochloride is a high-purity organic salt and a key pharmaceutical intermediate. This compound is valued for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of novel heterocyclic compounds.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex naphthyridine-based molecular architectures.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Potential utility in the development of enzyme inhibitors or receptor ligands due to its specific heterocyclic structure.

Basic Information

Product Name	Ethyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate Hydrochloride
CAS No.	1207175-08-3
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	Ethyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride; 1,7-Naphthyridine-3-carboxylic acid, 5,6,7,8-tetrahydro-, ethyl ester, hydrochloride; Ethyl 1,2,3,4-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride; 3-Carbethoxy-5,6,7,8-tetrahydro-1,7-naphthyridine hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.