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tert-Butyl 3-(5-Chloro-1H-Pyrrolo[3,2-B]Pyridin-2-Yl)Phenylcarbamate CAS NO 1206970-36-6


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CAS No.:1206970-36-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 3-(5-Chloro-1H-Pyrrolo[3,2-B]Pyridin-2-Yl)Phenylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and other targeted therapy areas.

Application

  • Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
  • Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and pharmacokinetic profiles.
  • Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes from laboratory to pilot plant and commercial production.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
  • Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name tert-Butyl 3-(5-Chloro-1H-Pyrrolo[3,2-B]Pyridin-2-Yl)Phenylcarbamate
CAS No. 1206970-36-6
Molecular Formula C18H18ClN3O2
Molecular Weight 343.81 g/mol
Synonyms tert-Butyl N-[3-(5-chloro-1H-pyrrolo[3,2-b]pyridin-2-yl)phenyl]carbamate; Carbamic acid, N-[3-(5-chloro-1H-pyrrolo[3,2-b]pyridin-2-yl)phenyl]-, 1,1-dimethylethyl ester; 3-(5-Chloro-1H-pyrrolo[3,2-b]pyridin-2-yl)phenyl carbamic acid tert-butyl ester; BOC-Protected 3-(5-Chloro-1H-Pyrrolo[3,2-B]Pyridin-2-Yl)Aniline; 1206970-36-6
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Quality Control

Our production of tert-Butyl 3-(5-Chloro-1H-Pyrrolo[3,2-B]Pyridin-2-Yl)Phenylcarbamate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 97.0%
Related Substances (HPLC) Individual impurity ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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