Description

4-Bromo-2-Chloro-6-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services (CDMO) and scale-up processes.
• Academic and R&D Laboratories: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Bromo-2-Chloro-6-Methylpyridine
CAS No.	1206250-53-4
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	2-Chloro-4-bromo-6-methylpyridine; 6-Methyl-2-chloro-4-bromopyridine; 4-Bromo-2-chloro-6-picoline; 2-Chloro-4-bromo-6-picoline; Pyridine, 4-bromo-2-chloro-6-methyl-; 4-Bromo-2-chloro-6-methylpyridine (primary CAS name)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.