Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Chloro-, Methyl Ester is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused bicyclic structure enables the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in kinase inhibitor and other targeted therapy programs.
• Agrochemical Development: Used in the creation of novel herbicides, fungicides, and insecticides that require specific heterocyclic cores for bioactivity.
• Chemical Research: Serves as a versatile building block in organic and medicinal chemistry for constructing complex polyheterocyclic systems.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Chloro-, Methyl Ester
CAS No.	1204475-99-9
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 3-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro-, methyl ester; 1204475-99-9; 3-Chloro-methyl pyrrolo[2,3-b]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Chloro-, Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.