Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Hydroxy- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies and small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and neurology research.
• Organic Synthesis Building Block: Used for constructing fused heterocyclic systems in medicinal chemistry and agrochemical research.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial labs for exploring new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Integral to the production pathway for novel APIs requiring the pyrrolopyridine scaffold.
• Bioconjugation & Probe Synthesis: The carboxylic acid and hydroxy functional groups allow for derivatization to create biochemical probes and labeled compounds.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Hydroxy-
CAS No.	1204475-87-5
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	3-Hydroxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Hydroxy-2-carboxy-7-azaindole; 3-Hydroxy-7-azaindole-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-hydroxy-; 3-Hydroxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1204475-87-5; 3-Hydroxy-7-aza-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.