Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-(Cyanomethyl)-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine core and strategically positioned cyano and ester functional groups. This compound is critical for medicinal chemistry research and development, offering a versatile scaffold for constructing complex bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Organic Synthesis: Used in the preparation of complex heterocyclic compounds for academic and industrial research.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Bioconjugation Chemistry: The reactive cyano and ester groups can be utilized for linking to biomolecules or other chemical moieties.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-(Cyanomethyl)-, Methyl Ester
CAS No.	1204475-79-5
Molecular Formula	C11H9N3O2
Molecular Weight	215.21 g/mol
Synonyms	Methyl 3-(cyanomethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 3-(Cyanomethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-(cyanomethyl)-, methyl ester; 1204475-79-5; Methyl 3-cyanomethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 3-Cyanomethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-(Cyanomethyl)-, Methyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.