Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Bromo- is a high-value brominated heterocyclic building block, specifically a functionalized azaindole derivative. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel small molecule therapeutics. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the creation of targeted kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of protein kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: Serves as a precursor for fluorescent probes or affinity labels targeting specific biological pathways.
• Agrochemical Research: Potential building block for developing new active ingredients with specific modes of action.
• Material Science: Exploration of novel organic electronic materials or metal-organic frameworks (MOFs) utilizing its unique heterocyclic structure.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Bromo-
CAS No.	1204475-66-0
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	3-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Bromo-7-azaindole-2-carboxylic acid; 3-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Bromo-2-carboxy-7-azaindole; 3-Bromo-2-carboxy-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (acid form); 3-Bromo-7-aza-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Bromo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.