Description

6-Bromo-3-Methyl-1,2,3,4-Tetrahydro-1,8-Naphthyridine is a high-purity, advanced pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex nitrogen-containing heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or metal complexation studies.
• Chemical Biology Probes: Acts as a core structure for creating molecular probes to study biological pathways and enzyme functions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	6-Bromo-3-Methyl-1,2,3,4-Tetrahydro-1,8-Naphthyridine
CAS No.	1204297-57-3
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	6-Bromo-3-methyl-1,2,3,4-tetrahydro-1,8-naphthyridine; 3-Methyl-6-bromo-1,2,3,4-tetrahydro-1,8-naphthyridine; 1,2,3,4-Tetrahydro-6-bromo-3-methyl-1,8-naphthyridine; 6-Bromo-3-methyl-1,2,3,4-tetrahydro[1,8]naphthyridine; 1204297-57-3; 6-Bromo-3-methyl-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS 1204297-57-3)
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Methyl-1,2,3,4-Tetrahydro-1,8-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.