Description

2-Pyridinamine, 4-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-2-Yl)- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in oncology and kinase inhibitor research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop next-generation therapeutic agents, leveraging its unique fused heterocyclic structure to modulate drug potency and selectivity.

Application

• Pharmaceutical Intermediate: Primary use as a core scaffold in the research and development of kinase inhibitors for targeted cancer therapies.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical precursor in the multi-step synthesis of investigational new drugs (INDs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the efficacy and pharmacokinetic profiles of lead compounds.
• Biochemical Reagent: Employed in biochemical assays as a reference standard or probe to study specific enzymatic pathways and protein interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	2-Pyridinamine, 4-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-2-Yl)-
CAS No.	1203569-39-4
Molecular Formula	C12H9ClN4
Molecular Weight	244.68 g/mol
Synonyms	4-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)pyridin-2-amine; 4-(4-Chloro-7-azaindol-2-yl)-2-aminopyridine; 2-Amino-4-(4-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)pyridine; 4-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-pyridinamine; 4-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)pyridine-2-amine; 4-(4-Chloro-7-azaindol-2-yl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Pyridinamine, 4-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-2-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.