Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-4-(1H-Pyrazol-4-Yl)- is a high-purity advanced pharmaceutical intermediate (API) with significant value in modern drug discovery and development. This compound is specifically engineered to serve as a critical building block in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other biologically active compounds, where its unique fused heterocyclic structure is essential.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Drug Discovery Scaffold: Used as a core structural motif in medicinal chemistry for building compound libraries and optimizing lead candidates.
• Biochemical Research: Employed in proteomics and high-throughput screening (HTS) assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for investigating structure-activity relationships (SAR) of heterocyclic compounds.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-4-(1H-Pyrazol-4-Yl)-
CAS No.	1203568-85-7
Molecular Formula	C10H7FN4
Molecular Weight	202.19 g/mol
Synonyms	5-Fluoro-4-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-(1H-pyrazol-4-yl)-7-azaindole; 4-(5-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazole; 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-4-(1H-pyrazol-4-yl)-; 1203568-85-7; 5-Fluoro-4-(pyrazol-4-yl)-7-azaindole; Azaindole-pyrazole derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-4-(1H-Pyrazol-4-Yl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pre-clinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.