Description

(E)-Methyl 3-(2-Aminopyridin-3-Yl)Acrylate CAS NO 1203500-12-2 is a high-purity, functionalized acrylate derivative featuring a 2-aminopyridine moiety. This compound is a critical pharmaceutical intermediate and versatile chemical building block for synthesizing complex molecules. It is essential for research and production in medicinal chemistry, particularly for developing kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor drugs.
• Medicinal Chemistry Research: A versatile building block for constructing compound libraries and exploring structure-activity relationships (SAR).
• Organic Synthesis: Used in Michael addition reactions, cyclizations, and other transformations to create heterocyclic compounds.
• Agrochemical Development: Intermediate for creating novel crop protection agents and pesticides.
• Material Science: Potential monomer or cross-linker for designing functional polymers with specific optical or electronic properties.

Basic Information

Product Name	(E)-Methyl 3-(2-Aminopyridin-3-Yl)Acrylate
CAS No.	1203500-12-2
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	Methyl (2E)-3-(2-Amino-3-pyridinyl)-2-propenoate; (E)-Methyl 3-(2-Amino-3-pyridyl)acrylate; Methyl (E)-3-(2-Aminopyridin-3-yl)acrylate; 2-Propenoic acid, 3-(2-amino-3-pyridinyl)-, methyl ester, (2E)-; 3-(2-Aminopyridin-3-yl)acrylic acid methyl ester; Methyl 3-(2-aminopyridin-3-yl)acrylate (E-isomer)
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(2-Aminopyridin-3-Yl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E/Z Ratio)	≥ 98:2 (E/Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.