Description

3-(4-Chloropyridin-3-Yl)Prop-2-Yn-1-Ol is a high-value, multi-functional chemical intermediate featuring a chloropyridine core linked to a propargylic alcohol moiety. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials due to its reactive alkyne and alcohol groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	3-(4-Chloropyridin-3-Yl)Prop-2-Yn-1-Ol
CAS No.	1203499-62-0
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	3-(4-Chloro-3-pyridinyl)-2-propyn-1-ol; 4-Chloro-3-(3-hydroxy-1-propynyl)pyridine; 3-(4-Chloropyridin-3-yl)prop-2-yn-1-ol; 4-Chloro-3-(prop-2-yn-1-yloxy)pyridine (isomer); 3-(4-Chloro-3-pyridyl)propargyl alcohol; Propargyl alcohol, 3-(4-chloro-3-pyridinyl)-; 1203499-62-0
EINECS	Contact for details

Quality Control

Our 3-(4-Chloropyridin-3-Yl)Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.