Description

8-Bromo-2,3-Dihydro-1H-Pyrido[3,4-B][1,4]Oxazine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Employed as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-2,3-Dihydro-1H-Pyrido[3,4-B][1,4]Oxazine
CAS No.	1203499-19-7
Molecular Formula	C7H7BrN2O
Molecular Weight	215.05 g/mol
Synonyms	8-Bromo-2,3-dihydro-1H-pyrido[3,4-b][1,4]oxazine; 1H-Pyrido[3,4-b][1,4]oxazine, 8-bromo-2,3-dihydro-; 8-Bromo-1,2,3,4-tetrahydropyrido[3,4-b][1,4]oxazine; 8-Bromotetrahydropyrido[3,4-b][1,4]oxazine; 8-Bromo-THPO; 8-Br-THPO; 8-Bromo-3,4-dihydro-2H-pyrido[3,4-b][1,4]oxazine
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,3-Dihydro-1H-Pyrido[3,4-B][1,4]Oxazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.