Description

4-(Benzyloxy)-3-Iodopyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a benzyl-protected oxygen and an iodine atom, makes it an indispensable reagent for constructing complex molecules through cross-coupling reactions. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine core is a common pharmacophore.
• Material Science Research: Employed in the creation of organic ligands for catalysis and in the synthesis of functionalized polymers or liquid crystals.
• Cross-Coupling Reactions: The iodine atom serves as an excellent handle for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to introduce the pyridine moiety into complex architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	4-(Benzyloxy)-3-Iodopyridine
CAS No.	1203499-10-8
Molecular Formula	C12H10INO
Molecular Weight	311.12 g/mol
Synonyms	3-Iodo-4-(phenylmethoxy)pyridine; 4-Benzyloxy-3-iodopyridine; 3-Iodo-4-benzyloxypyridine; 4-(Benzyloxy)-3-iodopyridine; Pyridine, 3-iodo-4-(phenylmethoxy)-; 1203499-10-8; 4-O-Benzyl-3-iodopyridine
EINECS	Contact for details

Quality Control

We supply 4-(Benzyloxy)-3-Iodopyridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.