Description

tert-Butyl 2-Chloro-5-Methylpyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine and carbamate functional groups. This compound is a critical building block in modern organic synthesis, enabling the development of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly in medicinal chemistry research and API development.
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of advanced pesticides and herbicides.
• Chemical Research & Development: Used as a versatile reagent in academic and industrial R&D for constructing heterocyclic compounds.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing specialized fine chemicals for clients.
• Process Chemistry: Employed in route scouting and optimization for scalable manufacturing processes.
• Ligand & Catalyst Development: Potential use in the development of novel ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	tert-Butyl 2-Chloro-5-Methylpyridin-3-Ylcarbamate
CAS No.	1203498-98-9
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	tert-Butyl (2-chloro-5-methylpyridin-3-yl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-chloro-5-methylpyridine; 2-Chloro-5-methylpyridin-3-amine, N-BOC-protected; BOC-2-Chloro-5-methyl-3-aminopyridine; tert-Butyl N-(2-chloro-5-methyl-3-pyridinyl)carbamate; 2-Chloro-5-methyl-3-pyridinylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-5-Methylpyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.