Description

2-Bromo-1-(2-Fluoropyridin-4-Yl)Ethanone is a high-purity fluorinated pyridine derivative and a versatile bromoacetyl intermediate. This compound is critical for introducing specific molecular fragments in advanced synthetic pathways, enabling the development of novel chemical entities. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive bromoacetyl group.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes and affinity tags used in proteomics and target identification studies.
• Material Science Research: Employed in the synthesis of specialized ligands and monomers for advanced polymers and functional materials.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in various palladium-catalyzed and other metal-mediated cross-coupling reactions.

Basic Information

Product Name	2-Bromo-1-(2-Fluoropyridin-4-Yl)Ethanone
CAS No.	1202854-31-6
Molecular Formula	C7H5BrFNO
Molecular Weight	218.03 g/mol
Synonyms	2-Bromo-1-(2-fluoropyridin-4-yl)ethan-1-one; 4-Acetyl-2-fluoropyridine, 2-bromo-; 2-Bromo-1-(2-fluoro-4-pyridinyl)ethanone; 2-Fluoro-4-(2-bromoacetyl)pyridine; 2-Bromo-2'-fluoro-4'-pyridyl methyl ketone; α-Bromo-2-fluoroisonicotinyl ketone; Ethanone, 2-bromo-1-(2-fluoro-4-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(2-Fluoropyridin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.